Diethyl isobutyroylmalonate
Diethyl isobutyroylmalonate
CAS: 21633-78-3
Molecular Formula: C11H18O5
Diethyl isobutyroylmalonate - Names and Identifiers
Diethyl isobutyroylmalonate - Physico-chemical Properties
| Molecular Formula | C11H18O5 |
| Molar Mass | 230.26 |
| Boling Point | 115°C/ 4mm |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Oil |
| Color | Colourless |
| Storage Condition | Refrigerator, under inert atmosphere |
| Sensitive | Irritant |
| MDL | MFCD00048557 |
Diethyl isobutyroylmalonate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
Diethyl isobutyroylmalonate - Introduction
Diethyl isobutyroylmalonate(Diethyl isobutyroylmalonate) is an organic compound with the chemical formula C12H20O5.
The following is a description of the properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: Diethyl isobutyroylmalonate is colorless to yellowish liquid.
-Solubility: It can be dissolved in many organic solvents, such as alcohols and ethers, and is almost insoluble in water.
Use:
-Chemical synthesis: Diethyl isobutyroylmalonate is an important compound that can be used in organic synthesis, for example, as an intermediate for the production of carboxylic acids according to Knoevenagel condensation reactions. In addition, it can also be used to synthesize organic compounds such as drugs and plant protection agents.
-Fragrance and fragrance formula: It can also be used as a synthetic intermediate for fragrance compounds.
Preparation Method:
Diethyl isobutyroylmalonate can be prepared by the following steps:
1. reacting diethyl malonate with isobutyryl chloride to generate diethyl isobutyryl malonate.
2. Further reaction to generate Diethyl isobutyroylmalonate.
Safety Information:
- Diethyl isobutyroylmalonate is generally stable under normal conditions of use, it may be irritating to the eyes, skin and respiratory system.
-Avoid direct contact during handling and wear appropriate protective measures, such as chemical protective gloves and masks, if necessary.
-Follow the relevant safety guidelines and regulations when using and storing chemicals.
Please note that the above information is for reference only. The specific experimental operation and safety precautions shall be subject to the specific requirements and information of the laboratory.
The following is a description of the properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: Diethyl isobutyroylmalonate is colorless to yellowish liquid.
-Solubility: It can be dissolved in many organic solvents, such as alcohols and ethers, and is almost insoluble in water.
Use:
-Chemical synthesis: Diethyl isobutyroylmalonate is an important compound that can be used in organic synthesis, for example, as an intermediate for the production of carboxylic acids according to Knoevenagel condensation reactions. In addition, it can also be used to synthesize organic compounds such as drugs and plant protection agents.
-Fragrance and fragrance formula: It can also be used as a synthetic intermediate for fragrance compounds.
Preparation Method:
Diethyl isobutyroylmalonate can be prepared by the following steps:
1. reacting diethyl malonate with isobutyryl chloride to generate diethyl isobutyryl malonate.
2. Further reaction to generate Diethyl isobutyroylmalonate.
Safety Information:
- Diethyl isobutyroylmalonate is generally stable under normal conditions of use, it may be irritating to the eyes, skin and respiratory system.
-Avoid direct contact during handling and wear appropriate protective measures, such as chemical protective gloves and masks, if necessary.
-Follow the relevant safety guidelines and regulations when using and storing chemicals.
Please note that the above information is for reference only. The specific experimental operation and safety precautions shall be subject to the specific requirements and information of the laboratory.
Last Update：2024-04-09 15:18:09
